摘要
目的探讨意外伤害多发儿童的神经生化特征，为筛选事故倾性儿童提供依据。方法 采用病例对照研究方法对７１对事故倾性儿童和安全组儿童外周血神经递质和激素水平进行分 析。结果事故倾性儿童体内儿茶酚胺类神经递质相比于安全组儿童普遍偏低，其中５－羟吲哚乙 酸和多巴胺水平差异显著，而两组儿童体内性激素、甲状腺激素的水平未发现有显著差异。结论 事故易发儿童发生意外伤害的行为可能与其体内儿茶酚胺类物质活性有关。
Object To research neurobiochemical characteristics of accident-prone children so as to provide related bases for screening accident-prone children. Method A case-control study on neurotransmitter and hormone levels in blood of 71 pair accident-prone children and non-accident children. Results Neurotransmitter concentration of catecholamine in blood of accident-prone children is universally lower than that of non-accident children, especially, SHIAA and DA of catecholamine. However , there is no significance in concentration of sexual hormone , and thyroxine in blood is between accident-prone children and nonaccident children. Conclusiou There are some relations between accidentprone children's behavior causing unintentional injury and cate-cholamine activity in their blood.
出处
《中华疾病控制杂志》
CAS
1999年第1期13-15,共3页
Chinese Journal of Disease Control & Prevention
基金
国家自然科学基金!39370601
关键词
事故倾性
儿童
儿茶酚胺
神经递质
激素
病例对照研究
accident-proneness
child
catecholamine
neurotransmitter
hormone
case-control study
