草绿色链球菌A19抑制脑膜炎双球菌生长的机理研究

Study on the mechanism for streptococcus viridans A19's inhibiting the growth of neisseria meaningitidis

目的探索草绿色链球菌Ａ１９抑制脑膜炎双球菌生长的机理。方法采用半定量接种， 活菌与死菌不同生长阶段的草绿色链球菌Ａ１９抑菌效果比较的方法。结果抑制作用由草绿色 链球菌Ａ１９的代谢产物引起，且稳定持久。结论揭示从草绿色链球菌Ａ１９的代谢产物中提取抑 菌成分的可能性。

Objective To explore the mechanism for streptococcus viridans A19's inhibiting the growth of neisseria menigitidis A19. Methods Incubacted living or dead streptococcus viridans A19 by semi-qualtity, specific analysis effection of anti-bacteria in the different growth stages. Result The inhibitory activity was caused by metabolite of streptococcus viridans A19 and was stable. Conclusion it was proposed that a chemical substance could be extracted from the metabolite and used in clinical practice.