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转化生长因子-β在肝纤维化形成中的作用及意义 被引量:1

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摘要 转化生长因子-β(TGF-β)是一类多肽生长因子,最初发现它们能促进成纤维细胞转化,后来认识到它们能调节细胞增殖、细胞外基质合成、血管形成及胚胎发生等。近年来研究认为TGF-β能刺激肝纤维化细胞外基质合成,在肝纤维化形成中起中心作用。 一、TGF-β及其受体 TGF-β是一个大家族,它的成员可分为三大类:TGF-βs。
出处 《实用肝脏病杂志》 CAS 1999年第4期247-249,共3页 Journal of Practical Hepatology
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