破伤风抗毒素结果判断及脱敏法的研究

Judgment of improved tetanus antitoxin hypodermical test and research about desensitation

对３５０例急诊外伤１～２４ｈ以内及破伤风发病住院２ｈ内需注射破伤风抗毒素（ＴＡＴ）的患者进行试验观察，按常规标准判断阳性率高达７１％以上。用作者提出的标准判断，阴性率占５１．４２％，真阳性占２％，假阳性占４６．５７％。采用改进的皮试液判断标准及脱敏注射法注射后，有效地降低了临床上ＴＡＴ皮试阳性率，增加了患者用药机会，患者痛苦小，减轻了护士的工作量及材料的消耗，药物吸收快，及时中和抗原获得有效免疫力。此法安全可靠，３５０例中被判断为假阳性者给予ＴＡＴ１５００Ｕ注射后无１例过敏反应。预防治疗率达９８％以上，全部通过临床应用。

The authors have undergone observation over 350 cases emergency injury within 1～24 hours and with tetanus incidence who are supposed to accept TAT,71% positive rate according to common standard,negative rate is 51 42% according to improved standard,real positive is 2%,pseudo positive is 46 57% This method enhance the chance of TAT use,and it is safe Those with pseudo positive test result have accept 1500U TAT without any hypersensative reaction preventive,curative rate is 98%,valuable to spread