The Synthesis of Podophyllotoxin Derivatives with Macrocyclic Dilactone

The Synthesis of Podophyllotoxin Derivatives with Macrocyclic Dilactone

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摘要 Starting from podophyllotoxin, five new derivatives with macrocyclic dilactone 5 similar to 9 have been synthesized,and their structures were confirmed by IR, MS,H-1 NMR as well as HRMS. The key step is cyclization by high dilution method. Starting from podophyllotoxin, five new derivatives with macrocyclic dilactone 5 similar to 9 have been synthesized,and their structures were confirmed by IR, MS,H-1 NMR as well as HRMS. The key step is cyclization by high dilution method.

作者 Min YANG Ning CHEN Xin Fu PAN Bing Chang QIN(Department of Chemistry. National Laboratory of Applied Organic Chemistry,Lanzhou University, Lanzhou, 730000)(Department of chemistry, Anyang Teachers College. Anyang 455002)

出处《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第4期275-276,共2页 中国化学快报（英文版）

关键词 podophyllotoxin DERIVATIVES macrocyclic dilactone SYNTHESIS podophyllotoxin derivatives macrocyclic dilactone synthesis

分类号 O629 [理学—有机化学]

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Chinese Chemical Letters

1999年第4期

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The Synthesis of Podophyllotoxin Derivatives with Macrocyclic Dilactone

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