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A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities 被引量:2

A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities
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摘要 A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. Its structure was determined as 1 (beta), 2 (beta), 9 (a) -triacetoxy-8 (a) -((a) -hydroxyl-isobutyryloxy)-15-benzoyloxy-4 (a) -hydroxy-dihydroagarofuran by means of NMR, MS and IR spectral analysis. Preliminary biological study on antitumor activity revealed that this compound showed strong nonselective cytotoxicity against four of the NCI panel cell lines. A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. Its structure was determined as 1 (beta), 2 (beta), 9 (a) -triacetoxy-8 (a) -((a) -hydroxyl-isobutyryloxy)-15-benzoyloxy-4 (a) -hydroxy-dihydroagarofuran by means of NMR, MS and IR spectral analysis. Preliminary biological study on antitumor activity revealed that this compound showed strong nonselective cytotoxicity against four of the NCI panel cell lines.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第6期487-490,共4页 中国化学快报(英文版)
关键词 Celastrus angulatus sesquiterpene polyol ester NMR antitumor activities Celastrus angulatus sesquiterpene polyol ester NMR antitumor activities
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