三阶梯药物治疗原发性肝癌疼痛

Treatment by three-step analgesic ladder for pain of primary liver cancer

目的:评价三阶梯药物治疗癌痛计划对原发性肝癌疼痛的疗效.方法:对29例中晚期原发性肝癌患者采用三阶梯用药方法按序、按时治疗癌性疼痛.结果:完全缓解(CR)19例(占65.52%),部分缓解(PR)3例(占10.35%),轻度缓解(MR)3例(占10.35%),有效率86.22%,无缓解(NR)4例(占13.78%),疗效优于单用哌替啶组,两组之间有非常显著差异(P<O.01).结论:中晚期肝癌有疼痛症状者应用三阶梯药物治疗,可减轻痛苦和提高生存质量.

ve: To assess the curative effect of three- step analgesic ladder on pain of primary liver cancer (PLC). Method: Twenty - nine patients with advanced PLC were treat-ed for cancerous pain by timely three-step analgesic ladder and the effects were analyzed. Result ;The complete relief ratio was 65.52 % ;the partial relief ratio was 10.35 % ;the mild relief ratio was 10.35 % ; the effective ratio was 86.22 % and the non-relief ratio was 13.78 % . The curative effect of three-step analgesic ladder was better than that in the control group by use of pethidine only. There was a statistically significant difference between the two groups in curative effects ( P < 0.01) . Conclusion: Three-step analgesic ladder has a good effect on pain relief and improvement of life quality in patients with intermediate or advanced cancer.