摘要
应用放射免疫法,检测了不同年龄感染腮腺炎合并睾丸炎患者的生殖激素水平变化。结果表明,3组患者均存在不同程度的生殖激素紊乱,尤其以青春期发生感染的组Ⅱ有显著性改变。与对照组比较,组Ⅱ的睾酮(T)水平显著降低,促卵泡刺激素(FSH)和黄体生成素(LH)分别升高2.87和1.97倍,催乳素(PRL)和雌二醇(E2)分别增加1.81和1.98倍。提示感染腮腺炎性睾丸炎患者的生殖激素有明显改变,且与感染时患者的年龄密切相关,这类患者存在生育障碍。
The present study was carried out to investigate changes in levels of the major hormones reglating the process of reproduction in patients with mumps orchitis by using a radioimmunoassay, Twenty two patients were divided into three groups according to the age when the patients were infected with mumps orchitis as a complication of parotitis epidemica infection. The results showed that there were marked changes in synthesis and secretion of studied hirmones in these three groups, expecially in patients who were infected during puberty (groupⅡ ). Comparing with the control group, plasma LH, FSH prolactin and estradiole level in group Ⅱ were significantly increased with 1 .97, 2. 87, 1. 81 and 1. 98 fold, respectively. Testosterone was significantly decreased. All hormones changes closely with severe morphological and functional alterations of testes and caused fertile problem in Patients with mumps orchitis. (Supported by grant L 714/1997 of Ministiy of SCience and Education, Bulgaria)
出处
《暨南大学学报(自然科学与医学版)》
CAS
CSCD
1998年第S1期44-47,共4页
Journal of Jinan University(Natural Science & Medicine Edition)
基金
保加利亚科学与教育部基金
关键词
激素
血浆
睾丸炎
人
hormones
plasma
mumps orchitis
men