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扶正化瘀方抗肝纤维化作用的药效学配伍机理研究(摘要) 被引量:2

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摘要 将临床抗肝纤维化有效的扶正化瘀方按扶正化瘀治法进行拆方,分为扶正组、化瘀组、虫草组、丹参组及丹参+虫草组,采用灌胃给药后分离药物血清方法,观察各组药物血清对体外培养大鼠肝星状细胞增殖与活化、Ⅰ型胶原mRNA的表达与胶原的分泌、TGFβ<sub>1</sub>mRNA及其蛋白的表达,肝细胞白蛋白合成等的影响。
出处 《中西医结合肝病杂志》 CAS 1998年第S1期410-410,共1页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
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同被引文献15

  • 1孙自勤,权启镇,于峻基.转化生长因子β_1(TGF-β_1)与肝纤维化[J].临床肝胆病杂志,1993,9(4):184-186. 被引量:11
  • 2王宝恩,赵洪涛,王泰玲,刘遵昌,贾继东,任万华.复方861对肝炎肝纤维化疗效的病理组织学分析[J].中华肝脏病杂志,1997,5(2):77-78. 被引量:58
  • 3Bachem MG,Meger D,Melchior R,et al.Action of rat liver perisinusoidal lipocytes by tranforiming growth factors derived from myofiblastlike cells A potential mechanism of self perpetuation in fibrogenesis. The Journal of Clinical Investigation . 1992
  • 4Czaja MJ,Weiner FJ,Flanders KC,et al.In vitro and in vivo association of transforming growth factor β with hepatic fibrosis. The Journal of Cell Biology . 1989
  • 5Eghbali Fatourechi G,Sieck GC,Prakash YS.Type 1 procollagen production and cell proliferation is mediated by transfroming growth factor-bate in a model of hepatic fibrosis. The Journal of Endocrinology . 1996
  • 6Blazejewski S,Preaux AM,Mallat A.Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver. Hepatology . 1995
  • 7Tuker RF,Shipley GD,Moss HL,et al.Growth inhibitor from BSC-1 cells is close related to the platelet type β tramforing growth factor. Science . 1984
  • 8Achem MG,Sell M,Melchior R.Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1(TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts. . 1993
  • 9Weiner FR,Shah A,Biempica L.The effects of hepatic fibrosis on Ito cell gene expression. Matrix . 1992
  • 10蔡卫民,陈峰.近年来肝纤维化主要新进展(上)——发病机理研究[J].临床肝胆病杂志,1998,14(2):65-68. 被引量:51

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