卵巢无性细胞瘤的治疗

The clinical study and treatment of ovarian Dysgerminoma

我院自1976—1992年收治了卵巢纯型无性细胞瘤40例，平均年龄24土7．8岁，多见于30岁以下的青年妇女。主要症状为腹部肿物、腹胀、腹痛，部分伴有腹水。除1例仅行手术外，其余均接受手术加放射治疗或化疗。5年生存率为90％。术后放疗、化疗的5年生存率分别为90％、88．9％，表明两种治疗都非常有效。年青患者为保留生理、生育功能或晚期患者以化疗为佳。

40 patients with pure dysgerminoma were admitted in our hospital fr0m l976- l992.The mean age 0f this serise was 24l 7. 8. Most of them (77- 5 % ) were under 30-years old- Abdom-ina1 mass was most comm0n symptom,sometimes with abdominal pain and distension, ll of 40 pa-tients with ascites. 26(65. 0% ) cases were stage I, 6 stage I, 5 stage m and 5 stage N. Exceptingone patlent was treated only by operation,all patients were treated by surgery with radiotherapy f0rchern0therapy. The 5wyear survival rate was 90%- The main prognostic factor was clinical staging.The surviva1 rate of postoperative radiotherapy and postoperative chernotherapy had no significantdifference. They were 9O. O% and 88. 8% respectively. It indicated that both surgery with radiothera-py and chemotherapy were very effective therapeutic measure, but for young patients who wanted tokeep their genetic function and advanced patients, operation with adjuvant chemotherapy might bebetter.