运动诱发电位在脊髓中传导通路及应用价值

THE EXPERIMENTAL STUDY OF CONDUCTION PATHWAYAND THE SIGNIFICANDE OF MEP IN SPINAL CORD

目的：研究经颅磁刺激（ｔｉｒａｎｓｃｒａｎｉａｌｍａｇｎｅｔｉｃｓｔｉｍｕｌａｔｉｏｎ，ＴＭＳ）运动诱发电位（ｍｏｔｏｒｅｖｏｋｅｄｐｏｔｅｎｔｉａｌ，ＭＥＰ）在脊髓中的传导通路。方法：采用兔的脊髓部分切断伤模型进行ＴＭＳ－ＭＥＰ监测，并与体感诱发电位相比较。结果：脊髓前索损伤时ＭＥＰ消失，侧索损伤时ＭＥＰ消失或潜伏期延长，后索损伤时潜伏期轻度延长。结论：ＴＭＳ－ＭＥＰ可准确的监测脊髓的前侧索损伤并可间接反映脊髓后索损伤。

Objective:To study the conduction pathway of transcranial magnetic stimulation motor evoked potential (TMS-MEP)in spinal cord and its clinical significance by experimental method.Methods:TMS-MEP was used in experimental study to monitor spinal cord function of partly cut spinal cord and to compare with sensory evoked potential(SEP).Results:TMS-MEPs was absent after the injury of anterior columns of spinal cord, absent or delayed after the injury of lateral columns of spinal cord.Conclusions:TMS-MEPs was conducted through anterior and lateral columns of spinal cord while SEP through posterior column of spinal cord. TMS-MEP was an effective method to monitor spinal cord injury.