恶性肿瘤并发深静脉血栓形成18例临床分析

MALIGNANT TUMOR COMPLICATED WITH DEEP VEIN THROMBOSIS

目的：探讨恶性肿瘤与深静脉血栓形成（ＤＶＴ）之间的关系，提高对恶性肿瘤并发ＤＶＴ的认识。方法：分析１８例恶性肿瘤并发ＤＶＴ病人的临床表现、血栓形成的部位、原发肿瘤的类型、彩色多普勒检查及溶栓治疗的效果。结果：恶性肿瘤并发髂股静脉血栓形成１５例（１５／１８，占８３％），血管阻塞的程度平均为８４％，原发肿瘤的第１位是肺癌，占３９％；其次，是胃肠道癌，占２８％。溶栓治疗后肿胀的肢体周径仅比治疗前缩小平均为１．８ｃｍ。结论：恶性肿瘤可能使血液凝固性增高，而导致ＤＶＴ；对无明显诱因的ＤＶＴ患者，都应注意是否由于恶性肿瘤所致；

Objective:To analyse the relation ship between malignant tumor and deep vein thrombosis (DVT). Methods: 18 cases of malignant tumor complicated with DVT were analysed in respect their clinical symptoms and signs, location of thrombosis, the type of primary tumor, and the effect of thrombolysis. Results:Of 18 cases, 15 cases (83%) suffered from illiofemoral vein thrombosis with the average stenosis rate of 84%. Lung cancer was found in 7 cases (39%). After thr/ombolysis therapy, the caliber of the limbs of the patients with malignant tumor, decreased 1 to 2.5 cm, while that of the patients without tumor decreased 3 to 5.5 cm. Conclusions:The relation ship between malignant tumor and DVT is close, and malignant tumor may result in hypercoagulation and causes DVT. We should pay attention to the DVT patients with unknown causes, because it may be the complication of malignant tumor. The effect of anticoagulation and thrombolysis therapy in the cases with malignant tumor as worse than that in the patients of DVT without malignant tumor.