158例食管癌术后复发转移的预后多因素分析

The Prognostic Factors for Recurrence/Metastases after Esophageal Resection for Cancer

通过对158例食管癌术后复发转移患者影响生存的预后因素进行多因素分析,结果表明肿瘤浸润深度和淋巴结转移是影响预后的重要因素,性别和辅助放疗对预后影响不大,作者认为,颈部吻合术的预后较胸内吻合好,放疗+化疗可能延长复发转移患者的生存期。

We examined the prognostic factors that influence survival of 185 patients who developed recurrence/metastases after curative resection for esophageal cancer.The 0.5- ,1- ,2- ,3- ,and 4- year overall survival rate were 70.7%,47.1% ,19.8%, 12.2% and 0%,respectively.The factors having significant difference were tested by Cox's multivaiate analysis to compare prognostic significance.The factors found to have significant differencel by univariate analysis were age, depth of invasion, lymph node metastasis, operatic procedure and different regiment of therapy in foreteen individual variables. Multivariate analysis showed that depth of invasion, lymph node metastasis, operative procedure and different regiment of therapy were significant prognostic factors. Sex and adjuant raadiotheray did not influence prognosis. We hold that esophagectomy with cervical anatomosis and radiotherapy plus chemotherapy may prolong surivial time of recurrence/metastases after esophageal resection for cancer.