低分子量肝素与潘生丁配合治疗急性早幼粒细胞白血病并发播散性血管内凝血

Effect of LMWH and Persantine in Treating Acute Promyelocytic Leukemia Complicated with DIC

目的:研究急性早幼粒细胞白血病(APL)合并播散性血管内凝血(DIC)的治疗方案。方法:使用全反式维甲酸加小剂量高三尖杉碱与阿糖胞苷作诱导缓解方式案,配合使用低分子量肝素与潘生丁治疗 DIC。结果:APL 20例合并 DIC全部逆转 (10％)。结论:本文认为本治疗方案确实安全有效。

Objective:To explore a treatment regimen for Apl complicated with DIC. Methods: Using All trans retinoid acid and low- dosage harringtonine plus Ara- C to achieve induced remisson. Meanwhile, LMPH and persantine were administrated to treat DIC. Results: The CR rate of the 20 APL cases was 80% , All had DIC and were reversed(100%) . Conclusion: This treatment regimen is thought to be safe and effective