摘要
To investigate the cellular immunological changes in children with viral hepatitis, interleukin 6 (IL-6), interleukin 8 (IL-8), interferon a (IFNα), and tumor necrosis factor α (TNFα) in supernatant of cultured peripheral blood mononu-clear cells (PBMCs) of 49 children with hepatitis A, B or C were measured. The levels of IL-6, IL-8, TNFα in PBMCs of the 3 viral hepatitis groups were increased and the level of IFNα decreased as compared with those of normal control group. But there were no significant differences among the 3 viral hepatitis groups. It was concluded that cellular immunological disorders were related to the onset and the induced damage of the viral hepatitis in children.
To investigate the cellular immunological changes in children with viral hepatitis, interleukin 6 (IL-6), interleukin 8 (IL-8), interferon a (IFNα), and tumor necrosis factor α (TNFα) in supernatant of cultured peripheral blood mononu-clear cells (PBMCs) of 49 children with hepatitis A, B or C were measured. The levels of IL-6, IL-8, TNFα in PBMCs of the 3 viral hepatitis groups were increased and the level of IFNα decreased as compared with those of normal control group. But there were no significant differences among the 3 viral hepatitis groups. It was concluded that cellular immunological disorders were related to the onset and the induced damage of the viral hepatitis in children.
