牛磺酸对脊椎外伤合并脊髓损伤的治疗作用

Therapeutic Effects on Spinal Cord Injury

从1993年2月～1997年7月共收治下胸椎、腰椎骨折脱位合并急性脊髓损伤患者92例,均急行伤段椎板切除,脊髓和神经根减压,CD器械内固定,横突间植骨融合术。术后随机分为牛磺酸治疗组和常规治疗对照组。牛磺酸组病人口服牛磺酸1g,每日3次,其余治疗同对照组。3个月后,神经功能按改良的Frankel分级评定,升高1级者为有效,统计结果用Radit分析,结果发现:术后牛磺酸组较对照组有显著性差异(P<0.05),说明牛磺酸对急性脊髓损伤有明显保护作用。

This study investigated the therapeutic effects of taurine on acute spinal cord injury deal to lowthoraco—lumbar vertibra fracture and dislocation. 92 patients treated from February 1993 to July 1997 were randomly divided in two groups, taurine group and control group. In taurine group, the patient took 3g taurine daily while 60mg VitB_1 in control group. Neuro—function was evaluated with the modified criteria of Frankel in 3 months. Rusult showed that taurine can significantly improve the patients' neuro-function compared with control group. As assistant therapeutic agent of spinal cord injury, taurine has clinical applied prospect.