The development and characterization ot recombinant adenovirus encoding RA538, p53 or p16 for gene therapy of cancer
The development and characterization ot recombinant adenovirus encoding RA538, p53 or p16 for gene therapy of cancer
摘要
We have constructed three recombinantadenoviruses encoding RA538, p53 or p16 respec-tively. These recombinant adenoviruses are able toexpress RA538, p53 or p16 in infected human cancercells. The transduction efficiency assay showed thatthe infected cancer cells inoculated with theserecombinant adenoviruses at MOI of 25 or greaterexhibited 100% transduction efficiency. The growthrates and colony formation of cancer cells infectedwith these recombinant adenoviruses were
出处
《中国实验血液学杂志》
CAS
CSCD
1997年第3期331-332,共2页
Journal of Experimental Hematology
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