树突状细胞接种——肿瘤免疫治疗的新策略
被引量:1
摘要
肿瘤的免疫学治疗方法一直得到广泛的研究。由早年的非特异性免疫增强剂到后来的LAK,TIL过继免疫治疗,随着基础免疫学对免疫应答、T细胞活化机制认识的逐步深入,人们对肿瘤免疫逃逸机制亦有了新的认识,进而产生了旨在增强肿瘤免疫原性治疗肿瘤的一系列新方法。这些新方法包括:将某些细胞因子基因转染人肿瘤细胞。
出处
《中国实验血液学杂志》
CAS
CSCD
1997年第1期52-57,共6页
Journal of Experimental Hematology
参考文献33
-
1Klein JL,Fickenscher H,Holliday JE,et al.Herpes virus saimiri immortalized γδT cell line activated by IL-12. J Immunol . 1996
-
2Thomas R,Lipsky PE.Dendritic cells: origin differentiation. Stem Cells . 1996
-
3Grabbe S,Beisert S,Schwarz T,et al.Dendritic cells as initiators of tumor immune responses: a possible strategy for tumor immunotherapy. Immunology Today . 1995
-
4Dranoff G,Jaffee E,Lazenby A,et al.Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proceedings of the National Academy of Sciences of the United States of America . 1993
-
5Huang AYC,Golumbek P,Ahmadzadeh M.Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science . 1994
-
6Steinman RM.The dendritic cell system and its role in immunogenicity. Annual Review of Immunology . 1991
-
7Austyn JM.New insights into the mobilization and phagocytic activity of dendritic cells. The Journal of Experimental Medicine . 1996
-
8Guery J-C,Ria F,Adorini L.Dendritic cells but not B cells present antigenic complexes to class Ⅱ-restricted T cells after administration of protein in adjuvant. The Journal of Experimental Medicine . 1996
-
9Alijagic S,Moller P,Artue M,et al.Dendritic cells generated from peripheral blood trans transtected with human tyrosinase induce specific T cell activation. European Journal of Immunology . 1995
-
10Porgador A,Gilboa E.Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T Iymphocytes. The Journal of Experimental Medicine . 1995
共引文献2
-
1赵明,毛宁,巴德年,张明伟,张学敏,周生,杜德林.逆转录病毒介导转导的人粒-巨噬系集落刺激因子基因在哺乳动物细胞中的表达(英文)[J].中国实验血液学杂志,1996,4(2):138-143. 被引量:1
-
2刘新垣.一个革命性的抗癌研究策略:癌症的靶向基因-病毒治疗[J].中国肿瘤生物治疗杂志,2015,22(2):159-165. 被引量:3
同被引文献9
-
1陈虎,楼晓,江岷,胡亮钉,俞志勇,徐晨,李渤涛,宁红梅,李欲航,冯凯,刘广贤.树突状细胞介导的抗白血病效应的临床研究[J].中国实验血液学杂志,2005,13(3):412-416. 被引量:9
-
2司图镇强 吴军正.细胞培养[M].世界图书出版公司,1996..
-
3André F,Schartz NE,Chaput N,et al.Tumor-derived exosomes:a new source of tumor rejection antigens.Vaccine,2002; 20:A28-31
-
4Zitvogel L,Fernandez N,Lozier A,et al.Dendritic cells or their exosomes are efective biotherapies of cancer.Eur J Cancer,1999; 35(Suppl 3):S36-S38
-
5Zitvogel L,Regnault A,Lozier A,et al.Eradication of established murine tumors using a novel cell-free vaccine:dendritic cell-derived exosomes.Nat Med,1998; 5:594-600
-
6MMorse MA,Garst J,Osada T,et al.A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer.J Transl Med,2005; 21:3-9
-
7Lamparski HG,Metha-Damani A,Yao JY,et al.Production and characterization of clinical grade exosomes derived from dendritic cells.J Immunol Methods,2002; 270:211-226
-
8Sozzani S,Allavena P,D' Amico G,et al.Differential regulation of chemokine receptors during dendritic cell maturation:a model for their trafficking properties.J Immunol,1998;161:1083-1086
-
9主鸿鹄,徐开林,潘秀英,刘军权,陈复兴,黄一虹.抗原冲击致敏的树突状细胞介导的特异性体外抗慢性粒细胞白血病细胞作用[J].中国实验血液学杂志,2003,11(3):278-281. 被引量:19
二级引证文献7
-
1陈绍倩,杜英,孙慧,孙玲,刘延方,董子明.外泌体联合CpGODN免疫刺激佐剂诱导CTL抗白血病效应[J].中国实验血液学杂志,2008,16(2):272-275. 被引量:3
-
2任亚娜,范华骅,聂晓绚,高跞,杨洁,刘嬿,高峰.树突状细胞外泌体免疫作用机制的初步研究[J].中国实验血液学杂志,2008,16(3):650-654. 被引量:7
-
3赵明峰,翟文静,邓琦,李玉明,耿丽,杨莉,吕海容,林雪梅,刘鹏江,李敬兰.白介素21对树突状细胞诱导的CTL抗白血病作用的影响[J].中国实验血液学杂志,2009,17(3):627-632. 被引量:5
-
4王英丽,张阳,徐广伟.负载乳腺癌抗原的脐血树突细胞外泌体抗肿瘤免疫作用[J].中国妇幼保健,2013,28(17):2774-2776. 被引量:3
-
5刘艳华,王小中.外泌体在疾病诊疗中的研究进展[J].实验与检验医学,2014,32(3):267-271. 被引量:11
-
6张娟娟,李瑞玮,贺继刚,欧阳红梅,撒亚莲.白血病细胞源外泌体的作用研究进展[J].中国病理生理杂志,2017,33(12):2287-2292. 被引量:4
-
7杜雪,郝梦哲,王昶,夏薇.骨髓间充质干细胞来源外泌体与血液病诊断[J].临床医药文献电子杂志,2017,4(22):4352-4353.
-
1胡渝华,沈惠云,万华靖.原癌基因、抑癌基因与肺癌研究现状[J].国外医学(卫生学分册),1999,26(3):138-142. 被引量:4
-
2宁波.肿瘤免疫与肿瘤免疫逃逸机制[J].中国实用妇科与产科杂志,2000,16(6):339-340. 被引量:3
-
3林奇,周士福.乳腺癌新辅助化疗研究进展[J].医学综述,2004,10(12):718-721. 被引量:3
-
4李琼.老年结肠癌患者术后早期EN对营养及免疫功能影响的观察及护理[J].中国现代医生,2012,50(32):97-99. 被引量:10
-
5付体辉,谢之荣.人类肿瘤主动免疫治疗研究进展[J].国外医学(肿瘤学分册),1993,20(5):285-287. 被引量:2
-
6董佑红(综述),伍钢(审校).NF-κB与肿瘤相关性的研究进展[J].世界肿瘤杂志,2006,5(3):216-220.
-
7刘丽燕,王兴鹏,姜立新,吴恺,杨佳芳.热休克蛋白70在赛来昔布联合热疗治疗胰腺癌中的作用[J].中华胰腺病杂志,2009,9(2):126-127.
-
8李海滨,范江河,董红霞.浅谈肿瘤的综合治疗[J].邯郸医学高等专科学校学报,2004,17(4):360-360. 被引量:1
-
9刘荣花,储以微.microRNAs在肿瘤免疫中的调控作用[J].生命科学,2012,24(5):415-420. 被引量:1
-
10黄慧强,管忠震.自体造血干细胞移植治疗恶性肿瘤进展[J].实用肿瘤杂志,2001,16(5):295-297. 被引量:3