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肟基磷酸酯类化合物及与氯硝柳胺复方增效的杀螺研究 被引量:23

MOLLUSCICIDAL EFFECTS OF OXIMINO PHOSPHATES AND SYNERGISM COMBINED WITH NICLOSAMIDE AGAINST SNAILS
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摘要 本文报道了24种肟基磷酸酯化合物的杀螺结果,发现化合物2、10、11和14等均具有杀螺作用,在25℃室温时,浸杀48h,1mg/L的杀螺率分别为100.0%、93.3%、83.3%和96.7%;LD50分别为0.6017、0.3969、0.7973和0.3260mg/L。将上述化合物与氯硝柳胺组成(1∶1)复方,化合物5和6与氯硝柳胺组成的复方均具有较好的增效杀螺作用,增效比(SR)值分别为2.32和3.50。 Molluscicidal effects of 24 compounds of oximino phosphates against Oncomelania hupensis hupensis were reported. The results showed that the compound 2, 10, 11 and 14 appered to have mollusclcidal effects. The snail mortalities of these compounds were 100.0 %,93. 3%, 83. 3% and 96. 7% and the LD50, was 0. 6017mg/L. 0. 3693mg/L, 0. 7973mg/L and 0.3260mg/L respectively at the concentration of 1mg/L, 25 ℃,, by immersion for 48 hours.Compound 5 and 6 cornbined with niclosamide In 1: 1 showed significant synergism against snails. The synergism rates (RS) were 2. 32 and 3. 50 respectively.
出处 《中国血吸虫病防治杂志》 CAS CSCD 1997年第1期1-4,共4页 Chinese Journal of Schistosomiasis Control
基金 "八.五"科技攻关课题!85-917-02-07
关键词 杀螺剂 氯硝柳胺 增效剂 肟基磷酸酯 Molluscicide, Niclosamide, Synergist, Oximino phosphates
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  • 1韩广甸,有机制备化学手册.上,1977年
  • 2马维勇,医药工业,1987年,18卷,428页
  • 3团体著者,有机合成.1,1957年

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