梗塞性脑血管病事件相关电位研究

STUDY ON EVENT-RELATED POTENTIALS IN PATIENTS WITH CEREBRAL INFARCTION

脑血管病是老年期痴呆的常见原因。脑梗塞患者约有2％～5％出现智能障碍。利用听觉刺激序列诱发的事件相关电位(P_(300)),对32例脑梗塞患者进行了临床研究。32例患者采用长谷川智测量表(HDS)评分。其中9例小于20分,其P_(300)潜伏期与正常对照组均延长,而23例HDS评分正常者其中10例P_(300)潜伏期延长。研究结果提示利用事件相关电位检测技术可早期发现脑梗塞患者亚临床痴呆。

Cerebrovascular disease was a common cause of dementia in the elderly.Cognitive impairment may be occured in 2-5% patients with cerebral infarction.We studied the event-related potentials (ERP) P300 waves evoked by auditory serial stimulus in 32 patients with cerebral infarction and compared with the normal subjects.Prolonged latency of P300 was seen in 9 patients with Hassagawa Dementia Screening Score (HDS)<20 and 10 cases in 23 patients with normal HDS.The study suggests that ERP is useful in detecting subclinical dementia in patients with cerebral,infarction.