刺五加制剂的人体抗疲劳试验与小鼠负重游泳试验的比较

The comparation of anti-fatigue test of human and weight carrying swimming experiment of mice on Ciwujia (Acanthopanax senticosus)preparation.

为研究刺五加制剂的抗疲劳作用，在小鼠游泳试验基础上于１６名健康成年男子中研究递增运动负荷下刺五加制剂对人体运动能力的影响。结果表明，服用刺五加制剂后可提高无氧阈下作功能力１２．４％；呼吸商由０．９９下降至０．８６，使运动时脂肪供能增加４３％。又在２０名大学生中进行持续恒定负荷运动测试，结果表明在４５０ｋｇ．ｍ／ｍｉｎ（７５Ｗ）时持速给予刺五加制剂１周可使运动时脂肪供能增加１０．２％，心率下降１０．３％，每搏摄氧量增加９．８％；而仅一次给予刺五加制剂组仅仅脂肪供能增加６．８％，其他指标没有改变这说明持续给试样优于仅仅一次给试样的结果。乳酸、心率和无氧阈的结果提示刺五加制剂无论对递增负荷运动还是持续恒定负荷运动人体，均能提高摄氧能力、节省肌糖元。

For study of the anti-fatigue effect of Ciwujia preparation, sixteen male adults' exercise tolerance were tested under increasing progressively sports, and the swimming experiment of mice had been done before. The results indicated intaking Ciwujia preparation could enhance work capacity of under-anaerobic threshold, the respiratory quotient decrease to 0.86 from 0.99 and the energy supplying from fat increase 43 percent. The detecting of continued constant carrying exercises under 450 kg.m/min of twenty university students showed that the energy supplying from fat during exercises increased 10.2 percent, the heart rate decreased 10.3 percent and the shock input of oxygen increased 9.8 percent after intaking Ciwujia preparation for a week while the energy supplying from fat increased 6.8 percent intaking the preparation only once. It proved the continous intaking better effect. The results of lactic acid, heart rate, anaerobic threshold pointed out that the preparation have anti-fatigue effect on human through increasing the capacity of oxygen input, saving muscle glycogen under either increasing progressively exercises or continuous constant carrying ones. Author's address Wu Yongning, Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medcine, Beijing 100050, PRC.