431例乙型病毒性肝炎患者血清中丁型肝炎病毒标志物的检测及临床意义

Detection and Clinical Significance of Serum Markers of Hepatitis D Virus(HDV) in 431 Cases with Hepatitis B

作者对我院431例各类型乙型病毒性肝炎患者血清进行了丁型肝炎病毒（HDV）标志物的检测及分析。结果显示：乙型肝炎患者中丁型肝炎病毒的感染率为4．6（20／431）；20例丁型肝炎患者其血清标志物HD-Ag、抗-HD－IgM及抗-HD的检出率分别为60．0％、70．0％及15．0％；乙肝与丁型肝炎病毒双重感染者其乙肝复制指标的检出率均显著低于单一乙肝感染者（P＜0．05）。

We detected the serum markers of hepatitis D virus (HDV) in 431 cases with hepatitis B. Theresult showed that the infection the of HDV was 4. 6% (20/431). The positive rates of HDAg. anti- HDV- IgM and anti- HDV in 20 cases with hepatitis D were 60%. 70% and 15%respectively. The positive rates of hepatitis B virus (HBV) replication markers in patients with HBVand HDV double infection were lower than the cases with only HBV infection (P<0. 05).