19例卵巢宫内膜异位症组织的性激素受体水平测定

Measurement of Steroid Receptors in Non-Diseased Endometriotic Ovary and of Serum Hormone Concentrations of the Patients

对40例非病性卵巢和19例卵巢宫内股异位症组织进行胞浆、胞核ER、PR、AR水平及外周血FSH、LH、Er、P、T水平的测定．结果显示：两组的ERn、PRn、ARn均显著高于ERc、PRc、ARc，两组的ERn与ER、PRn与PR比较，非病性卵巢组差异有显著性．卵巢宫内膜异位症组差异天显著性，说明非病性卵巢组的ERc与ERn、PRc与PRn之间存在一定的比例关系，而卵巢宫内膜异位症组其比例关系失调；卵巢宫内膜异位症组ERc显著低于非病性卵巢组，P与ERc、ER呈显著负相关，ERc与PRc呈显著正相关，说明卵巢宫内股异位症组织与宫腔内膜的性质相同，都受性激素的相同调节．

The forty Samples of the non-diseased ovaries and the nineteen tissues of the endometriotic ivaries were detected on cytosol and nuclear estrogen, progesterone and androgen receptor contents, and the levels of the serum FSH, LH, E2, P and T were also detected in these patients at time. The result indicated that the contents of ERC and PRC are certainly in proportion to those of ERn and PRn in non-diseased ovarian group, while the contents of ERc and PRc are not in proportion to those of ERn and PRn in the endometriotic ovaries. The level of serum progesterone was negatively correlated with that of ERc or ER, it was suggested that the property of the tissue cells in the Cvarian endometriosis was similar to that in normal uterine endometrium, both of them were umder the same control by sexual hormones.