摘要
采用测定大鼠额叶皮层电惊厥阈值作为指标的方法，观察柴胡的抗惊厥作用，发现柴胡的抗惊厥作用具有一定的量效关系，与抗惊厥西药安定比较，剂量较大，约为安定剂量的10倍，注射后3小时，阈值增加达最大值（231±112．52μA，均数±标准差），具有统计学意义（P＜0．05），6个小时后，这种意义依然存在，而且实验表明柴胡无明显的毒副作用。
We haVe studied the anticonvulsant effect of Chai Hu in freely rast using the method of the frontal cortical threshold test by direct cortical stimulation. The apriment shows that the anticonvalsant effect of Chai Hu has its dose - effect relation . Compared to antiepileptic drug valium , its dose is 10 times larger than that of valium .Its change of threshold attains the maximal amount (23l ±112.53μA, mean± sd) after three hours of injection.Ths increase is significant (P <0.05), and the effect still remains after 6hours . The experiment also shows tha Chai Hu has not poisonous side effect.
出处
《广州医学院学报》
1997年第1期24-26,共3页
Academic Journal of Guangzhou Medical College
关键词
柴胡
电惊厥阈值
额叶皮层
Chai Hu
Convulsant threshold
Frontal Cortex
