冠心病室性心律失常与左室功能关系

The relationship between ventricular Arrhythmia and left ven-tricularfunction with coronary disease

为了评价左室功能损伤对冠心病室性心律失常的影响.本文将接受选择性冠脉造影和左室造影的85例患者,同步进行24小时动态心电监测,记录24小时内室性早搏数并且按LOWN氏标准分级。按左室射血分数将受检查者划分为心功能正常组(EF≥60％),其中冠脉正常32例.心绞痛20例.心肌梗塞8例;心功能减退组(EF<60％),其中冠脉正常者2例、心绞痛2例和心肌梗塞21例。结果显示:①心功能减退组室性早搏的检出率96％(24/25)明显高于心功能正常组65％(39/60),P<0.005)。②心功能减退组冠心病室性早搏的检出率96％(22/23)同样显著高于心功能正常组71％(20/28).P<0.05。③心功能减退组≥3级的室性心律失常的检出率为29％,而心功能正常组为13％,前者有升高的趋势。初步认为窒性心律失常在人群中有较高的发生率。

In order to avaluate the effect of heart failure on ventricular arrhythmia with coronary artery disease,85 cases,underwent coronary angiography,left ventriculography and ambulatory ECG monitoring,were studied.The subjects were divided into two groups,left ventricular eject fraction(EF)≥60% group and EF<60% group.The were 32 cases with normal coronary artery,20 cases with angina pectohs and 8 cases with myocardial infarction in EF≥60% group,2,2 and 21 cases,respectively,in the other group.The parameters included the number of ventricular ectopic beats during 24 hours and the degree of ventricular arrhythmia according to I-own's standard.Results: 1.The incidence of ventricular arrhythmia was significantly higher in EF<60% group(96%)than that in EF≥60% group(65%),P<0.005.2.The incidence of ventricular arrhythmia with coronary artery disease was also significantly higher in EF<60% group(96%)than that in EF≥60 group(71%),P<0.05.3.The incidence of ventricular arrhythmia≥3 grade was not different in two groups,29% and 13%,respectively,P>0.05.It is concluded that ventricular arrhythmia is more common in human beings and heart failure is the important cause of ventricular arrhythmia with coronary disease.