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DIFFERENCES OF HEPATITIS B VIRUS SERUM MARKERS BETWEEN MALE AND FEMALE

DIFFERENCES OF HEPATITIS B VIRUS SERUM MARKERS BETWEEN MALE AND FEMALE
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摘要 By radioimmunoassay (RIA) method we tested 17 165 clinical cases of 8 kinds of hepatitis B virus (HBV) serum markers. There were more men than women in the data we counted up (2. 13: 1). Statistic results showed that positive HBV surface antigen (HBsAg) and HBV core antibody (anti-HBc) were more frequently found in male (P < 0.005). It implies that compared with women, men are HBV susceptible. We also found that in the admitted patients there were more males than females (P<0. 005). It means that no matter what kind of disease the patients suffered from,if co-infected with HBV, men would be more seriously ill. Other data present here showed: 1. Higher positive results or HBsAg/poly-human serum albumin receptor (HBsAg/Re) and HBV e antigen (HBeAg) in men (P <0. 005) demonstrated more active and infectious HBV male patients. 2-Higher positive rate of anti-HBc/IgM (HBcAb/IgM), HBsAg/IgM complex (HBsAg/IgM) in male (P<0. 005) indicated that more men were acute hepatitis B. 3. Lower frequency or anti-HBs in men (P<0.005) showed that male body immunoreaction was weaker than femare so the prognosis of men was worse than that of women. By radioimmunoassay (RIA) method we tested 17 165 clinical cases of 8 kinds of hepatitis B virus (HBV) serum markers. There were more men than women in the data we counted up (2. 13: 1). Statistic results showed that positive HBV surface antigen (HBsAg) and HBV core antibody (anti-HBc) were more frequently found in male (P < 0.005). It implies that compared with women, men are HBV susceptible. We also found that in the admitted patients there were more males than females (P<0. 005). It means that no matter what kind of disease the patients suffered from,if co-infected with HBV, men would be more seriously ill. Other data present here showed: 1. Higher positive results or HBsAg/poly-human serum albumin receptor (HBsAg/Re) and HBV e antigen (HBeAg) in men (P <0. 005) demonstrated more active and infectious HBV male patients. 2-Higher positive rate of anti-HBc/IgM (HBcAb/IgM), HBsAg/IgM complex (HBsAg/IgM) in male (P<0. 005) indicated that more men were acute hepatitis B. 3. Lower frequency or anti-HBs in men (P<0.005) showed that male body immunoreaction was weaker than femare so the prognosis of men was worse than that of women.
出处 《Journal of Pharmaceutical Analysis》 CAS 1997年第1期11-13,共3页 药物分析学报(英文版)
关键词 hepatitis B virus RADIOIMMUNOASSAY hepatitis B virus radioimmunoassay
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