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衰老与线粒体DNA缺失 被引量:1

Aging and MtDNA Deletions
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摘要 简略综述人体衰老过程中出现的线粒体DNA缺失,包括mtDNA与衰老的关系;衰老过程中的mtDNA容易变异的原因;衰老过程中发生的dmtDNA种类和数量改变等内容. It was briefly reviewed that mtDNA deletions occured in the human aping process.They involve the relations with mtDNA and aging, the courses that the deletions was easilybrought in the human aging process, and the varieties and quantity of the mtDNA deleted.
出处 《上海师范大学学报(自然科学版)》 1997年第3期54-59,共6页 Journal of Shanghai Normal University(Natural Sciences)
关键词 衰老 线粒体DNA(mtDNA) 线粒体DNA缺失 aging mitochondrainl DNA deletions in the mtDNA
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  • 1J. Miquel,A. C. Economos,K. G. Bensch,H. Atlan,J. E. Johnson.Review of cell aging in Drosophila and mouse[J]. AGE . 1979 (3)
  • 2O Zeviani M,Moraes C T,Dimauro S,Nakase H,Bonilla E,Schon E A,Rowland L P.Deletion ofmitochondrial DNA in Kearns-Save syndrome. Neurology . 1988
  • 3Yen T C,Pang C Y,Hsieh J H,Su C H,King K L,Wei Y H.Age-dependent 6 kb deletion in human livermitochondrial DNA. Biochemistry International . 1992
  • 4Cortopassi G A,Arnheim N.Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Research . 1990
  • 5Clayton D A,Doda J N,Friedberg E C.The absence of a pyrimidine dimer repair mechanism in mammalianmitochondria. Proceedings of the National Academy of Sciences of the United States of America . 1974
  • 6Richter C.Do mitochondrial DNA fragments promote cancer and ageing. FEBS Letters . 1988
  • 7Harman D.Ageing Theory based on free radical and radiation chemistry. Journal of Gerontology . 1956
  • 8Shoffner J M,Lott M T,Voljaver A S,Soueidan S A,Costigom D A,Wallace D C.Spontaneous KearnsSayre/Chronicexternal ophthalmoplegia plus syndrome associated with a mitocondrial DNA deletion:A slipreplication model and metabolic therapy. Proceedings of the National Academy of Sciences of the United States of America . 1989
  • 9Zhang C,Baumer A,Maxwell R J,Linnane A W,Nagley P.Multiple mitochondrial DNA deletions in anelderly human individual. FEBS Letters . 1992
  • 10Harman D.The biological clock:the mitochondria. J Am Geriatr,Soc . 1972

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