乙型肝炎病毒感染与原发性肝癌的关系

Correlation between Infection of Hepatitis B Virus and Primary Hepatic Carcinoma

本文观察了30例原发性肝癌(PHC)患者血清中乙型肝炎病毒(HBV)感染的五种指标的显示情况及既往罹患史.结果显示:PHC患者中HBsAg阳性率为70%.显著高于阴性率及对照组.而抗HBs的缺乏,说明体内未产生足够的免疫力.抗HBc-IgG的阳性率为73.33%,也显著高于阴性率,表明:HBV感染是PHC发病的主要危险因素,而IgG型核心抗体在慢性感染过程可能存在的时间更长,与PHC的关系更具特异性.所以对有过乙型肝炎病史,而HBsAg、抗HBc—IgG长期阳性,缺乏抗HBs的患者,应予以重视,以期能早期诊断PHC,提高治愈率.

In this paper, the authors made observations on five indices of infection of hepatitis B rirus in serum of 30 patients with primary hepatic carcinoma. The results showed that:The positive rate of HbsAg of PHC group was 70%, higher than negative rate and that of control group. The deffiency of HBs antibody indicated low immunity in the body. The positive rate of HBc-IgG antibody was 73.33%, higher than negative rate. It is suggested that the infection of HBV is one of the leading causes for the incidence of PHC. In the course of chronic infection, IgG nuclear antibody may exist for a long time, and it is specific for its correlation with PHC. Therefore, early diaghosis should be made to improve the cure rate.