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Effects of 24 Chinese Medicinal Herbs on Nucleic Acid, Protein and Cell Cycle of Human Lung Adenocarcinoma Cells

Effects of 24 Chinese Medicinal Herbs on Nucleic Acid,Protein and Cell Cycle of Human Lung Adenocarcinoma Cells
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摘要 Objective: To study the effects of 24 Chinese medicinal herbs on nucleic acid, protein and cellcycle of human lung adenocarcinoma cells. Methods: Using flow cytometry the authors analysed the effects of 24Chinese medicinal herbs (CMH) in compound recipe on proliferation index (PI), DNA index, protein index andratio of various phases in cell cycle of human lung adenocarcinoma cells (SPC-A-1). Results: The PI was morethan 20%, in 4 CMH, while 3 CMH, Gynostemma Pentaphylla, Radix Glehnia, and Radix Ginseng couldstrengthen the body resistance. That suggested using CMH of strengthening body resistance could not only serveas conventional ionic but also as tumor cell inhibitor. Meanwhile the action points of 24 CMH on cell cycle weredifferent from one another. Conclusions: According to these results, Chinese recipes were more effective in clinical practice. Objective: To study the effects of 24 Chinese medicinal herbs on nucleic acid, protein and cellcycle of human lung adenocarcinoma cells. Methods: Using flow cytometry the authors analysed the effects of 24Chinese medicinal herbs (CMH) in compound recipe on proliferation index (PI), DNA index, protein index andratio of various phases in cell cycle of human lung adenocarcinoma cells (SPC-A-1). Results: The PI was morethan 20%, in 4 CMH, while 3 CMH, Gynostemma Pentaphylla, Radix Glehnia, and Radix Ginseng couldstrengthen the body resistance. That suggested using CMH of strengthening body resistance could not only serveas conventional ionic but also as tumor cell inhibitor. Meanwhile the action points of 24 CMH on cell cycle weredifferent from one another. Conclusions: According to these results, Chinese recipes were more effective in clinical practice.
出处 《Chinese Journal of Integrative Medicine》 SCIE CAS 1997年第2期105-108,共4页 中国结合医学杂志(英文版)
关键词 Chinese medicinal herbs of strengthening body resistance flow cytometry lung cancer CELLCYCLE nucleic acid PROTEIN Chinese medicinal herbs of strengthening body resistance, flow cytometry, lung cancer, cellcycle, nucleic acid, protein
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参考文献2

  • 1吴善芳,苏建中,王恩忠,徐蕙萱,叶庆炜,徐昌文,陈瑞铭,叶秀珍,朱德厚,杨正洪.人体肺腺癌细胞系——SPC-A-1的建立及其生物学特性[J]中国科学(B辑 化学 生物学 农学 医学 地学),1982(10).
  • 2李仪奎.中药药理实验方法学[M]上海科学技术出版社,1991.

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