考核血吸虫病低度流行区血清学查病质量的方法学研究──Ⅰ.综合评估指标的研究

INVESTIGATION ON EVALUATION METHODOLOGY OF SERO-DIAGNOSIS OF SCHISTOSOMIASIS IN ENDEMIC AREAS WITH A LOW PREVALENCE──Ⅰ.COMPREHENSIVE INDEXES FOR EVALUATION OF SCHISTOSOMIASIS DETECTION

为研究查病质量的综合指标，我们应用质控血清进行COPT双盲试验，跟踪考核现场血吸虫病查病质量。结果24个县共检测质控血清1147份，实际诊断符合率为65．34％，期望诊断符合率为59．61％。7项指标的聚类分析将24个县的查病质量分成好、中、差3类单位。提示该评估方法对跟踪现场查病质量具有较强的实用性，并进一步筛选出K、E、I、DI4项主要指标，分类正确率高达95％以上，因而该4项指标拟可用于评估现场COPT查病质量。

The double blind tests of COPT with standard sera were carried out to trace the quality of field work on detection of schistosomiasis. The results showed that 1 147 standard sera were detected in 24 counties,the actual coincidence rate was 65. 34%,and expect coincidence rate was 59. 61 %. The 24 counties were divided into 3 groups (good,medium,bad) by cluster analysis depending on 7 comprehensive indexes representing the quality of schistosomiasis detection. More than 95% of cases were correctly classified by stepwise discriminant analysis depending on only 4 indexes,such as K,E,I,DI. It is indicated that these 4 comprehensive indexes can be used for evaluation of the quality of schistosomiasis detection.