糖尿病夜间血压下降率与脑血栓形成关系探讨

Study of the Relationship between NIDDM Patients Droping Rate of Asleep Blood Pressure and Cerebral Thrombosis

本研究采用无创性动态血压监测仪(ABPM)对82例非胰岛素依赖型糖尿病(NIDDM)患者进行24小时动态血压观察,按其夜间血压下降率是否正常,将受试者分为两组,统计对比脑血栓形成的发生率。结果表明:NIDDM患者夜间血压下降率<10％(即昼夜节律消失)时,脑血栓形成的发生明显增加,与对照组比较差异有显著性(P<0.01)。提示:NIDDM患者夜间血压下降率减少可能是器官缺血的一种表现形式,其出现与脑血栓形成发生呈负相关。

Observation of 24 hours ambulatory blood pressure(ABP) of 82 cases of NIDDM patients was carried out by using ABP monitor (ABPM). The patients were divided into 2 groups according to whether their droping rates of asleep blood pressure were normal. The rates of cerebral thrombosis of the groups were comparied. The results show that if the droping rate of the asleep blood pressure of patients is less than 10% (day - and - night rhythm vanish), cerebral thrombosis increase obviously. Compared with the normal group, there is significant difference(P< 0.01), the less the droping rate of the asleep blood pressure, the more the occurrence of cerebral thrombosis,and decreasing of the droping rate of asleep blood pressure can lead to the lack of blood in brain organs.