多发性腔隙梗塞患者血浆生长抑素含量的初步观察

A Preliminary Study of Somatostation Concentration in Plasma of Patients with Multiple Lacuna Infarcts

本文应用放射免疫法对20例多发性腔隙梗塞(MLI)患者及16名健康人的血浆生长抑素(SS)含量进行了观察,结果显示MLI患者血浆SS含量为17.16±4.86ng/L。较健康对照组(22.94±9.75ng/L)为低(P<0.05),提示SS含量降低与MLI有明显关系。其发生机理可能是下丘脑-垂体轴功能紊乱所致。

In this papar, radioimmunoassay was carried out to measure the somatostation (SS) concentration in 30 patients with mult tiple lacunar infarcts(MLI) and 16 normal controls. The mean concentration of plasma SS in patients with MLI was 7.16 ± 4. 86 ng/L, which was decreased as compared with that of normal controls whose mean SS concentration was 22. 94 ± 9.75 ng/L. It suggests that the reduction of SS concentration was obviously related to MLI. The mechanism may be associated with the fuctional disorder of the hypothalamus-hypophysis axis.