摘要
In mastectomy specimens, the primacy foci of occult breast carcinoma were usually examinated by routine bistopathologlcal method, but the result was not satisfactory. Tke detecting rates of primany foci were 50%-56% in China and 45%-75% in some other countries. In this study, whole organ subserial section was perforined in 20 cascs of occult breast cancer from April,1988 to February, 1994. Priniacy foci were found in 16cases (80%) by microscopic examination. Diaineters of 10foci were less than 1.0 cm with the smallest as 0.3×0.1×0.1 cm. In addibon, occult multiple foci were detected in 5cases (31.25%), which would be very difficult to be found by routine histopatkological examination. ER, PgR and monocloue M4G3 assays were performed for positive Iymph nodes to confirm the primary foci to be breast cancer. The possible causes for the failure of detection of the primary foti by whole organ section are discussed.
In mastectomy specimens, the primacy foci of occult breast carcinoma were usually examinated by routine bistopathologlcal method, but the result was not satisfactory. Tke detecting rates of primany foci were 50%-56% in China and 45%-75% in some other countries. In this study, whole organ subserial section was perforined in 20 cascs of occult breast cancer from April,1988 to February, 1994. Priniacy foci were found in 16cases (80%) by microscopic examination. Diaineters of 10foci were less than 1.0 cm with the smallest as 0.3×0.1×0.1 cm. In addibon, occult multiple foci were detected in 5cases (31.25%), which would be very difficult to be found by routine histopatkological examination. ER, PgR and monocloue M4G3 assays were performed for positive Iymph nodes to confirm the primary foci to be breast cancer. The possible causes for the failure of detection of the primary foti by whole organ section are discussed.
