羊搔痒症及其相关疾病病原体——Prion(朊病毒)

Pathogen of Scrapie and Associated Disease——Prion

朊病毒是羊搔痒症及其相关疾病如人的库鲁病、疯牛病及牛海绵状脑组织疾病的病原体。本文综述了朊病毒的理化性质、形态结构、组织分布、分离鉴定及其分子生物学研究的最新进展。

Prion is a pathogen which can cause scarip, human kuru, human ckeutzfeldtjakob disease (CJD) and bovine spone cerebral tissue. The paper deals with the physical and chemistry characters, formation and structure, tissue distribute and separate and identify of prion, and studing develepment of molecule biology of prion.