原发不育症子宫内膜花生凝集素受体的研究

A STUDY ON PNA RECEPTOR OF ENDOMETRIUM IN PATIENTS WITH PRIMARY INFERTILITY

本文以PNA(花生凝集素)为探针,应用ABC亲和组化技术,对69例原发不育症患者的子宫内膜PNA受体进行了检测.结果表明,原发不育症子宫内膜的增生期、分泌期PNA受体的阳性率均显著低于年龄相似、有生育史的对照组子宫内膜的阳性率.不育症子宫内膜分泌欠佳的PNA受体阳性率显著低于不育症分泌期不同时期子宫内膜的阳性率.提示,这种差异可能与雌孕激素对两组子宫内膜作用水平的不同引起.

Using affinity histochemical technique, with PNA as the probe, the authors examined endometrium of 69 cases with primary infertility. The results showed that the positive rate of PNA receptor in the female infertility at the stage of proliferation and secretion was much lower than that in the control group, that the positive rate of PNA receptor in the insufficient secretion of endometrium was lower than that in the early, middle and later secretory phase. These results indicate that the difference is related to the actions of estrogen and pro-gestin on endometrium.