PN配合生长抑素治疗急性坏死性胰腺炎的临床观察

Observation of PN combined with somatostatin in the treatment of acute necrotic pancreatitis

分析了在手术治疗基础上,对应用PN和生长抑素治疗急性坏死性胰腺炎的作用.根据临床分级、年龄及性别分成PN加生长抑素组,PN组和对照组(非PN组).以住院时间,合并症发生率、死亡率、血浆白蛋白及氮平衡变化为指标.结果显示:三组间各项指标以PN加生长抑素组最优(P<0.05—0.01),对照组最差.认为PN能改善急性坏死性胰腺炎病人营养状态.降低胰腺外分泌,配合生长抑素治疗,可进一步抑制胰腺分泌,使胰腺充分休息,有利于提高该病的临床疗效.

This report analyzed the actions of PN supporting and somatostatin in the combined treatment of acute necrotic pancreatitis. In this study, 91 patients were devided into three groups receiving PN+ somatostain,PN and non-PN by clinical typing,sex,age. The study indexs were hospitalization time, complication rate, mortality plasma album and nitrogen balance. The study result was that the most favour index was that in PN + somatostatin (P<0.05-0.01), and PN was second, the last was non-PN. It is concluded that PN could improve the nutritional status of the patients and inhibity the secretion of pancreas. Combined with somatostatin, PN could increase the inhibiting effect and make pancreas have an enough rest, which is beneficial to tissue repairment of pancreas, it could decrease mortality, prevent the complications and reduce the hospitalization time. So it is worth widespreading.