摘要
Using comparative molecular field analysis approach, the interaction of 17 tetrahydroprotdederines to D1 reccptor and15 ones to D2 reccptor have ben studied by 3D-QsAR. respectively. The results indicated that the interactions of THPBs withdopamine receplors were primarily clectrostatic interactions. with more positive charge in lignnd and more negative in receptor.
Using comparative molecular field analysis approach, the interaction of 17 tetrahydroprotdederines to D1 reccptor and15 ones to D2 reccptor have ben studied by 3D-QsAR. respectively. The results indicated that the interactions of THPBs withdopamine receplors were primarily clectrostatic interactions. with more positive charge in lignnd and more negative in receptor.
