血友病性骨假瘤—附8例报告

Hemophilic Pseudotumor——Report of 8 Cases

报告血友病性骨假瘤8例9个部位,其中血友病A 7例,血友病B 1例,患者均为男性,年龄8～24岁。位于股骨下段4例,指骨2例,趾骨1例,另1例在两个部位(指骨和跟骨)先后发病。多数有外伤史(占7/9)。4例5个部位发生干手或足骨者以局部膨胀性肿块为主要表现,其中3例继发皮肤溃破出血。4例股骨病变都在外伤后出现肿痛和畸形,其中3例继发病理性骨折。3个手指施行了截指术。跟骨病变采用放射治疗。文章对血友病性骨假瘤的发病机制,避免误诊,继发病理性骨折或浅表组织溃破出血的处理。放射治疗,手术治疗以及各种治疗方法的选择等问题进行了比较详细的讨论。

8 cases of hemophilic pseudotumor were hospitalized in our hospital from 1970 to 1992, among which there were 7 cases in hemophilia A and one in hemophilia B. All patients were male, aged from 8 to 24 years old. 4 cases occured at distal femur, 2 at finger, one at toe, and the another one at finger and calcaneus. Most of cases suffered from injury. Expansive mass existed locally in hand or foot, and ulceration and bleeding occured in 3 cases of finger or toe. Therewere swelling, pain and deformity at the thigh,and pathological fracture occured in 3 cases of femur. Amputation was performed in 3 fingers. Radiotherapy was for the case of calcaneus. The etiopathogenesis of hemophilic pseudotumor,the avoidance oi misdiagnosis, the treatment of secondary pathological fracture of the bone or ulceration and bleeding of the skin, radiotherapy,operation , and the selection of various therapies were discussed in detail.