先天性肾积水超微结构因素分析

Electronmicroscopic Observation of Ureteropeivic Junction of Congenital Hydronephrosis

对38例单纯先天性肾积水肾盂输尿管连接部(UPJ)组织作了透射电镜检查,其主要病理超微结构改变是平滑肌细胞间有大量胶原纤维组织堆积,平滑肌细胞相互分离,肌细胞本身发育不良,胞膜改变。线粒体肿胀破坏。积水的原因是UPJ部位功能性梗阻。

38 UPJ specimens excised surgically had been observed under eleccronmicroscopy. The main histopathologic change was an abundance of collagen fibers existing between smooth muscle cells, which were seperoted from one another by the fibers Vesiculation and swelling of. mitochondria with dysplasia of muscle cells were found. The cause of congenital hydronephrosis was functional obstruction of ureteropelvic junction. The abnormal UPJ tissue therefore should be excised as long as possible on operation.