摘要
Femoral veins of 17 mongrel dogs were distended with 40 kpa, 80 kpa and 120 kpa respectively prior to grafting to colateral femoral arteries. The sections were harvested at intervals of immediatness, 1 week, 4 week and 16 week followed with scanning electron microscopy (SEM) examination. The endothelial cells of grafted veins were investigated by computerized imaging analysis system. The results showed that desquamation extent of intimal layer correlated positively with the pressure. 80 kpa and 120 kpa caused relatively severe damage to the endothelium, which was significantly different from that of control group (P<0. 05). We conclude that preimplantation distention shooed be employed with less than 80 kpa, and 120 kPa shoud be avoided due to its damage to the development of reendothelialization. Nevertheless, the distension makes little notable impact to graft Patency rate as demonstrated in this experiment.
