摘要
AIMS To study the effect and safety of hepatic arte- rial embolization (HAE) with Bletilla Striata powders of traditional Chinese drug in the treatment of primary hep- atic carcinoma (PHC). METHODS From May 1990 to September 1993,106 patients with PHC were treated by HAE with Bletilla Striata powders (n=56) or gelfoam powders (n=50) respectively under the controlled technical conditions. Authors analyzed the effects and complications in two groups. RESULTS Bletilla Striata powders produced exten- sive permanent proximal embolization of hepatic artery and collateral circulation formed. Intermission of treat- ment was as long as 6-12 months and tumor necrosis and shrinking were obvious. The survival rates of 1,2 and 3 years were 81.9%,44.9% and 33.6% respec- tively and the mean survival time was 19.8 months without serious complications. All clinical effects of Bletilla Striata group were better than those of glfoam group. CONCLUSIONS Bletilla Striata powders are superi- or to gelfoam powders as an angioembolus for hepatic carcinoma.
目的研究中药白芨粉粒栓塞肝动脉治疗肝癌的疗效和安全性.方法从1990年5月-1993年9月,在相同条件下,分别使用白芨和明胶海绵颗粒栓塞肝动脉治疗肝癌56例和50例,分析两组的疗效和并发症.结果白芨粉粒具有强大的永久性,中心性栓塞血管作用,侧支循环形成少、时间晚;治疗间隔时间长,为6-12月;肿块坏死缩小显著,患者1,2,3年生存率分别为81.9%,44.9%,33.6%,平均生存期19.8月;无严重并发症发生.所有临床疗效均优于明胶组.结论中药白芨粉粒是一种较理想的肝癌血管栓塞剂.
基金
Supported by the National Natural Science Foundation of China,No.93019512.
