摘要
A third pyrimidine strand can bind the complementary purine strand of homopurinehomopyrimidine tracts of duplex DNA to form a local triplex structure. Recently investigations have indicated that triplex-forming-oligonucleotides can specifically inhibit gene transcription in vitro and in vivo, and can be used in chromosome analysis and
基金
the Eighth Five-Year Project Grant of Chinese Academy of Sciences and Natural Science Foundation of China.
