The design, synthesis, conformation and bioactivity of deltorphins analogues 被引量：1

The design, synthesis, conformation and bioactivity of deltorphins analogues

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摘要 Deltorphins are endogenous linear heptapeptides, isolated from skin extracts of frogs(genus phyllomedusa) in 1989, which have a higher affinity and selectivity for δopioidbinding sites than any other known natural compound. The analgesic activity,

作者王锐胡晓愚嘉庆姬虹王勤

机构地区 Department of Biology. State Key Laboratory of Applied Organic Chemistry

出处《Chinese Science Bulletin》 SCIE EI CAS 1995年第16期1342-1346,共5页

基金 Project supported by the National Natural Science Foundation of China, the State Education Commission of China and the National Laboratory for Dynamic and Stable State of Molecule.

关键词 deltorphins solid phase peptide SYNTHESIS 2D-NMR red cell IMMUNOLOGICAL COMPETENCE analgesia. deltorphins, solid phase peptide synthesis, 2D-NMR, red cell immunological competence, analgesia.

分类号 Q75 [生物学—分子生物学]

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1HUO Xiaofeng,WU Ming,REN Weihua,WANG Rui,CHAN Albert S.C..Structure-activity relationship of endomorphins and their analogs[J].Chinese Science Bulletin,2001,46(13):1096-1100.

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Chinese Science Bulletin

1995年第16期

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The design, synthesis, conformation and bioactivity of deltorphins analogues 被引量：1

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