摘要
Cholecystokinin octapeptide (CCK-8) in CNS has been shown to function as aneuropeptide with the most potent anti-opioid activity. It facilitates opioid tolerance andelectroacupuncture (EA) tolerance. Our previous study suggested that morphineadministration and EA stimulation can produce a marked increase of the CCK-8immunoreactivity (ir) in the perfusate of rat spinal cord. However, the problems
