100例扁桃体癌放射治疗分析

RADIATION THERAPY OF 100 PATIENTS WITH TONSILLAR CARCINOMA

1972年 5月至 1 988年 1 2月共收治疗 1 0 0例癌患者。全组均属病理证实 ,计未分化癌 31例 ( 31 % ) ,低分化癌 33例 ( 33% ) ,鳞癌 31例 ( 31 % ) ,腺癌 1例 ( 1 % ) ,乳头癌恶变 1例 ,未分类3例。临床分期 :( 1 987,UICC)Ⅰ期 4例 ( 4 % ) ,Ⅱ期 6例 ( 5 % ) ,Ⅲ期 2 1例 ( 2 1 % )及Ⅳ期 6 9例( 6 9% )。颈部淋巴结转移 :N0 1 8例 ( 1 8% ) ,N1～ 3 82例 ( 82 % )。远距离60 Co照射 5 0～ 70Gy/6～ 8周 ,占 88% ,1 2例患者照射量 <5 0Gy。随诊超过 5年者 93例。 1 ,3,5年生存率分别为 76 0 %( 70 /1 0 0 )、 5 3 0 % ( 5 3/1 0 0 )和 4 9 4 % ( 4 6 /93)。分期早者预后好 ,总剂量大于 6 0Gy为宜 ,年青患者生存率高 ,放疗结束时肿瘤消失者预后好。

100 patients suffering from cancer of the tonsil were treated by radiation therapy from May 1972 through 1988. All were proved by pathology as: anaplastic carcinoma 31(31%), poorly differentiated carcinoma 33(33%),squamous cell carcinoma 31(31%), adenocarcinoma 1(1%), papilloma with malignant change 1 and unclassifiable 3. Cliniral staging (1987,UICC) stage Ⅰ4(4%), stage Ⅱ6(5%), stage Ⅲ 21(21%) and stage Ⅳ 69(69%). N 0 18(18%),N 1～3 82(82%).Telecobalt was given to 50～70 Gy/6～8wk in 88% of patients. It was <50 Gy in 12 patients .The 1-, 3-and 5-year survival rates were 76% (76/100),53%(53/100) and 49.4%(46/93).