摘要
用中药复方益气消症冲剂进行减轻放疗毒性反应的实验研究 ,主要观察本冲剂对小鼠放疗期间白细胞 ,骨髓造血机能和肝肾功能的影响。结果证明 ,中药益气消症冲剂对放射引起的骨髓抑制有明显的保护作用。照射 3次的中药加放疗组小鼠的白细胞和骨髓细胞计数均明显高于单纯放疗组 ,统计学有显著差异 (P <0 .0 0 1 ,P <0 .0 0 5 )。放疗后 3周 ,单纯放疗组小鼠的肝、肾功能明显升高 ,而中药加放疗组小鼠的肝、肾功能则均正常。说明中药益气消症冲剂对小鼠放疗期间的肝、肾功能有明显保护作用。
In order to evaluate the effect of chinese medicine (Yi Qi Xiao Zheng decoction) in reducing radiation side effect, an observation of peripheral blood WBC, stem cell amount, the function of liver and renal in mice was made during and after radiation.The results showed that WBC and stem cell amount were higher in Chinese medicine combined with radiation group than radiation only group after 3 fraction radiation(P<0.001 andP<0.005, respectively). Radiation 3 weeks later, the liver and renal functions of mice in radiation only group were markedly growing higher, but they were normal in chinese medicine combined with radiation group. Our experiment certificates that Yi Qi Xian Zheng decoction can clearly protect the stem hematopoietic function, liver and renal function. At the same time, radiotherapy combine with Yi Qi Xiao Zheng decoction, can reduce the side effect of radiation.
出处
《中华放射肿瘤学杂志》
CSCD
1995年第2期42-43,82,共3页
Chinese Journal of Radiation Oncology