摘要
Primary neuroendocrine carcinoma of the skin (Merkelcell tumor), a rare malignancy originating from the skin,has only been established in the recent years. 1It has a main predilection on the skin in the head and neck region with an obvious tendency of local recurrence and early metastasis.Histopathologically, it resemble the neuroendocrine carcinoma from other sites of the they in morphology,immuno-histochemistry and ultrastructure. Diagnosis of the tumor is quite difficalt. Based upon two of our cases as verified by electron microscopy and / or immunohistochemistry, the clinical and pathological features of this tumor are discribed and the literature reviewed.
Primary neuroendocrine carcinoma of the skin (Merkelcell tumor), a rare malignancy originating from the skin,has only been established in the recent years. 1It has a main predilection on the skin in the head and neck region with an obvious tendency of local recurrence and early metastasis.Histopathologically, it resemble the neuroendocrine carcinoma from other sites of the they in morphology,immuno-histochemistry and ultrastructure. Diagnosis of the tumor is quite difficalt. Based upon two of our cases as verified by electron microscopy and / or immunohistochemistry, the clinical and pathological features of this tumor are discribed and the literature reviewed.
