摘要
Ａｓｔｕｄｙｏｆｐｏｉｎｔｍｕｔａｔｉｏｎｏｆｒａｓｇｅｎｅｓｉｎｈｕｍａｎｇａｓｔｒｉｃｃａｎｃｅｒ￥ＷａｎｇＪｕｎｒｕ（王俊茹）；ＬｉｕＷｅｉｗｅｎ（刘为纹）；ＤｅｎｇＧｕｏｒｅｎ（邓国仁）；ＬｕＹｏｕｙｏｎｇ（吕有勇）；ＷａｎｇＸｉｎ（王欣）（...
The point mutation at codons 12 and 61 of c-Ha-ras gene,at codon 12 of N-ras gene and at codons 12 and 13 of K-ras gene was observed in formalin-fixed and paraffin-embedded tissue specimens of 42 cases of gastric cancer with PCR-RFLP method. It was found that the point mutation at codon 12 of c-Ha-ras occurred in 14 cases out of the 42(33. 3%) and that at codon 12 of K-ras in 2 cases(4. 8%). Statistical analysis showed that the point mutation of ras genes plays an itnportant role in the prognosis for the patients with gastric cancer.
