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Synthesis and Antitumor Activity of Poly-L-Lysine Containing 5-Fluorouracil as Pendent Group

Synthesis and Antitumor Activity of Poly-L-Lysine Containing 5-Fluorouracil as Pendent Group
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摘要 Homopolymers of L-amino acids such as poly(L-glutamic acid) and poly (Llysine) not only have good biocompatibility and biodegradability, but also lack of immunogenicity. It has been reported that homopoly(L-amino acids) were used as the carriers of antitumor drugs such as mustard, methotrexate (MTX), cyclophosphamide, daunomycin(DM) and adriamycin (ADR). 5-Fluorouracil(5-FU) is most useful for the treatment of patients with carcinoma of the breast and gastrointestinal
出处 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 1990年第3期244-248,共5页 高等学校化学研究(英文版)
关键词 POLY-L-LYSINE 5-FLUOROURACIL Antitumor Activity Polymeric drug Poly-L-Lysine, 5-Fluorouracil, Antitumor Activity, Polymeric drug
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