摘要
用PGL-ELISA与GPAT对照研究,检测了47例麻风病人、103名麻风家内接触者、15例活动性结核和100名非流行区正常人的血清抗PGL抗体水平,结果表明二试验有较高的符合率,且GPAT抗体滴度与PGL-ELISA抗体OD值之间有较好的相关性。100名正常人和15例结核病人的阳性率分别为5％和6.7％,多菌型和少菌型麻风病人的阳性率分别为93.3％和59.8％,与PGL-ELISA相比,GPAT是一项简便快速、具较好特弹性和敏感性的麻风筛检试验。但为了适应现场实验的需要,应进一步探讨用干血滤纸片法做GPAT,以提高其敏感性。
A comparative study of GPAT and PGL-ELISA was made on 47 leprosy cases. 103 household contacts, 15 tuber- culosis patients and 100 normal per- sons. The results show that the positive rate for normal persons from non end- emic areas is 5% and tuberculosis pa- iients is 6.7%, multibacillary and pau- cibacillary leprosy patients are 93.3% and 59.8%. There was a high degree agreement in the two tests as well as antibody level (r=0.80-0.83 P0.0005), Although specificity and sensitivity of GFAT is lower than PGL-ELISA it is ample enough for field work. Therefore. it can he concluded GPAT is of practi cal value for the detection of leprosy hut further studies to improve its sen- sitivity is required.
出处
《中国麻风皮肤病杂志》
北大核心
1990年第2期74-78,共5页
China Journal of Leprosy and Skin Diseases
